PhD project opportunity – funded by Czech Science Foundation (GACR) 2025-2027
Project descriptionTranscription factors of the basic helix-loop-helix Per-Arnt-Sim (bHLH-PAS) family are critically important for animal development and physiology. Certain bHLH-PAS proteins are intracellular sensors or receptors of small molecules including environmental xenobiotics, pesticides, or endogenous metabolites and hormones. Insects possess a unique signaling system with a sesquiterpenoid juvenile hormone (JH) that activates a bHLH-PAS receptor (JHR) through …