Group leader
Roman Tuma
principal investigatorVirus assembly and molecular machines
HPLC and solution scattering techniques
rtuma at prf.jcu.cz
(+420)-38-777-6235
C 01 026
Part time also at University of Leeds, U.K.
Research interests
1. Virus assembly – dsRNA viruses/Avian reovirus, viral factories/viroplasms
2. Mechano-chemical coupling in molecular motors that translocate along nucleic acids and polypeptides e.g. viral ATPases and SecYEG/SecA
3. Assembly of bacteriochlorophylls and structure of light harvesting antennae – chlorosomes
4. Single molecule fluorescence and optical imaging techniques
We apply combination of advanced biophysical and structural techniques to study self-assembly and function of large macromolecular complexes such as viruses, Sec translocon, helicases and light harvesting complexes. Key biological processes that are studied in our group: RNA packaging and segment assortment in dsRNA viruses of the Reoviridae family; mechanism and dynamics of hexameric helicases and SecA driven polypeptide translocation across membranes. We also use self-assembly of bacterial photosynthetic pigments to create hybrid quantum dot nanostructures for applications in synthetic biology and nanophotonics.Project manager
Renata Krinesová
project managerrkrinesova at prf.jcu.cz
(+420)-38-777-5576
Project Department, ÚMBR BC AV, 3rd floor
Researchers
Filip Dyčka
Reasearch interests: proteomics, MS
Facility responsibility: Mass Spectrometry
fdycka at prf.jcu.cz
(+420)-38-777-6242
C 01 044
Tomáš Fessl
single-molecule fluorescencefessl at prf.jcu.cz
(+420)-38-777-6238
C 01 038
Zdeněk Franta
molecular biologyzfranta at prf.jcu.cz
(+420)-38-777-6230
C 01 019
Zdeno Gardian
Cryo-EMgardian at prf.jcu.cz
(+420)-38-777-5459
Laboratory of EM
Part time also at Institute of parasitology BC, ASCR
David Kaftan
Research interests: photosynthesis, spectroscopy, AFMFacility responsibility: AFM
dkaftan at prf.jcu.cz
(+420)-38-777-6227
C 01 016
Part time also at Institute of Microbiology ASCR
Peter Konik
mass spectrometrykonik at prf.jcu.cz
(+420)-38-777-6242
C 01 044
Ivana Kutá-Smatanová
Research interests: protein crystallogenesis and crystallography
Facility responsibility: X-ray
C 01 025
Part time also at the Institute of Microbiology ASCR, Nove Hrady
David Řeha
computational chemistryreha at nh.cas.cz
(+420)-38-777-6231
C 01 020
Part time also at the Institute of Microbiology ASCR, Nove Hrady
Post Docs
Barbora Kaščáková
Mol-bio and structural studies of sigmaNS and P4 proteins
barbora.karrafova at gmail.com
barbora.karrafova at gmail.com
C 01 024
PhD students
Eva Ďurinová
Cryo Electron Microscopy in Structural Studies of Biological Specimen.
Supervisor: Zdeno Gardian
evadurinova12 at gmail.com
Supervisor: Zdeno Gardian
evadurinova12 at gmail.com
Laboratory of EM
Petra Havlíčková
Structural studies of TBEV NS proteins.
Supervisor: doc. RNDr. Ivana Kutá-Smatanová, Ph.D.
havlickova.pet at seznam.cz
Supervisor: doc. RNDr. Ivana Kutá-Smatanová, Ph.D.
havlickova.pet at seznam.cz
C 01 024
Štěpánka Tomková
![](http://makrokomplex.cz/wp-content/uploads/2021/08/received_10211267253108406-208x300.jpeg)
The role of TBEV nonstructural proteins on the virus replication
Supervisor: Zdeněk Franta
tomkos00 at prf.jcu.cz
Supervisor: Zdeněk Franta
tomkos00 at prf.jcu.cz
C 01 019
Lab Technician
Šárka Petáková
Lab technician
petaks00 at prf.jcu.cz
(+420)-38-777-6227
C 01 016
MSc Students
BSc Students
Florian Goetzl
Kristýna Čtveráčková
Alumni
Joel Crossley
single-molecule fluorescence
joelcrossley at hotmail.com
Paulina Duhita Anindita
Molecular Biology and protein crystallography
anindita.duhita at gmail.com
![](http://makrokomplex.cz/wp-content/uploads/2021/08/Pavel-150x150.jpg)
anindita.duhita at gmail.com
![](http://makrokomplex.cz/wp-content/uploads/2021/08/Pavel-150x150.jpg)
Pavel Grinkevich
Protein crystalloraphy and molecular biology
pavel.grinkevich at gmail.com
pavel.grinkevich at gmail.com